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Invokana

Invokana Kidney Failure, FDA Strengthens Warning

By | Invokana, Uncategorized

Invokana diabetic ketoacidosisInvokana has been a familiar subject in US Food and Drug Administration (FDA) safety releases as of late. In the past year, the FDA issued safety updates on Invokana and diabetic ketoacidosis, serious urinary tract infections, amputation, and kidney failure. The latest warning, which the FDA issued in mid-June 2016, is about Invokana kidney failure.

According to the strengthened warning, the kidneys can suddenly stop functioning in people using Invokana, Invokamet, canagliflozin (generic equivalent), and dapagliflozin. If the kidneys stop functioning, the body is unable to flush waste, resulting in a dangerous accumulation of waste in the body.

The FDA’s strengthened warning came after the regulatory agency received just over 100 adverse event reports relating to Invokana and kidney failure. Adverse event reports are submitted to the FDA to report injuries from a drug or medical device.

Invokana Amputation

In May 2016, the Invokana attorneys at Carey Danis & Lowe covered the FDA’s warning on Invokana amputation. The FDA issued the amputation warning after reviewing data from an ongoing study.

Do you have an Invokana lawsuit?

Ask an Invokana attorney at Carey Danis & Lowe about your case. We offer free, no obligation case consultations.

Call 800.721.2519, or complete our confidential online form.

FDA Warns of Invokana Amputation

By | Invokana, Uncategorized

Invokana diabetic ketoacidosisData from an ongoing study revealed a risk of amputation among people taking the diabetes drug Invokana. This data prompted the US Food and Drug Administration (FDA) to release a safety update about Invokana, and the version of the drug with metformin, Invokamet, in mid-May 2016.

The study—Canagliflozin Cardiovascular Assessment Study (CANVAS)—followed participants for almost 5 years. During that period, researchers found a twofold increase in the risk of amputation among participants taking Invokana versus a placebo.

About 7 out of every 1,000 participants taking 100 mg of Invokana (canagliflozin) per day underwent amputation. The risk lowered slightly in participants taking 300 mg of Invokana per day and in those taking a placebo.

Amputation of legs, feet, and toes were most common among CANVAS participants.

Invokana has also been linked to diabetic ketoacidosis, a serious condition that often requires hospitalization, and is potentially fatal.

Do you have an Invokana case?

You can find out if filing an Invokana lawsuit is right for you by asking a Carey Danis & Lowe attorney. We offer free, no obligation case evaluations. Call 800.721.2519, or complete our confidential online form.

Invokana Ketoacidosis & Kidney Failure

By | Invokana, Uncategorized

Invokana diabetic ketoacidosisPeople with Type 2 diabetes take Invokana, or the version with metformin—Invokamet, to regulate blood sugar levels. Treating Type 2 diabetes with medication, along with improved diet and exercise, is important; however, in the case of Invokana and Invokamet, the risks may outweigh the benefits.

What is Invokana?

Invokana is a sodium-glucose co-transporter-2 (SGLT2) inhibitor. It is only FDA-approved to treat Type 2 diabetes, not Type 1.

Invokana side effects

Invokana is linked to diabetic ketoacidosis. This occurs when the body overproduces a blood acid, called a ketone. Ketoacidosis is a serious condition that can result in hospitalization.

Ketoacidosis symptoms include:

  • Abdominal pain
  • Confusion
  • Dehydration
  • Fatigue
  • Trouble breathing
  • Vomiting

The US Food and Drug Administration issued a warning about diabetic ketoacidosis in May 2015. And adding to that warning, the FDA mandated that drug makers update warning labels to include information about ketoacidosis.

The FDA also required drug makers to begin postmarketing studies on ketoacidosis and patient health.

Another Invokana side effect is urinary tract infection that can cause kidney failure. People who used Invokana, and suffered kidney failure, ended up being hospitalized for their injuries.

We can help.

Do you have an Invokana case?

We can help you determine if filing an Invokana lawsuit is the right decision. Our law firm offers free, no obligation case evaluations.

Contact Carey Danis & Lowe today. Call 1-800-721-2519, or complete our confidential online form.